appearing in scattered or isolated instances, as a disease. Rare and scattered in occurrence.quotations ▼ 2.1. It has been found that prions transmit three ways: obtained, familial, and sporadic. (Benign Adrenal Gland Pheochromocytoma, NCI Thesaurus) It may be a sporadic lesion or part of Brooke-Spiegler syndrome. Credit: Wikipedia Research at the Buck Institute shows the same mechanisms that lead to neuronal cell death in mice genetically fated to develop Parkinson's disease (PD) … Sporadic refers to a disease that occurs infrequently and irregularly. Sporadic Diseases. 2. A sporadic disease occurs now and then at low levels. This assumption cannot be tested, but other comparisons can assess its veracity. Meningitis is an acute inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges. An endemic disease is one which is constantly present in a given area, though usually at low levels, whereas an epidemic is widespread and has a high incidence. See more. All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. It has also been found that plants play the role of vector for prions. CJD is sometimes called a human form of "mad cow disease" (bovine spongiform encephalopathy, or BSE).BSE is actually a cause of one rare type of Creutzfeldt–Jakob disease; the two are not the same disease. It might be outdated or ideologically biased. Sporadic definition, (of similar things or occurrences) appearing or happening at irregular intervals in time; occasional: sporadic renewals of enthusiasm. Cancer is a common disease, so most families will have some members who have had cancer. Denoting a temporal pattern of disease occurrence in an animal or human population in which the disease occurs only rarely and without regularity. Antonyms for sporadic. Applying outbreak-based attribution estimates to nonoutbreak foodborne illnesses requires an assumption of similar exposure pathways for outbreak and sporadic illnesses. * (English Citations of "endemic") Used of a disease or condition: Most cancers are sporadic, caused by genetic mutations that are not heritable. Infectious diseases such as polio, cholera, smallpox and tuberculosis have historically caused sporadic epidemics of devastating proportions. In the genetic context, sporadic denotes a … sporadic contact. Other symptoms include confusion or altered consciousness, vomiting, and an inability to tolerate light or loud noises. Definition of sporadic in the Definitions.net dictionary. The disease, known also as Sydenham's chorea (not to be confused with Huntington's disease Huntington's disease, hereditary, acute disturbance of the central nervous system usually beginning in middle age and characterized by involuntary muscular movements and progressive intellectual deterioration; formerly called Huntington's chorea. Hyperendemic refers to persistent, high levels of disease occurrence. Creutzfeldt–Jakob disease (pronounced KROITS-felt YAH-kohb) or CJD is a neurological disease.It is degenerative (it gets worse over time); it cannot be cured, and it always causes death. Synonyms for sporadic in Free Thesaurus. These epidemic diseases are frequently spread through person-to-person contact, but they also commonly occur due to contaminated food. sporadic disease A disease that occurs occasionally in a population. Researchers have identified a mechanism that appears to underlie the common sporadic (non-familial) form of Parkinson’s disease, the progressive movement disorder. 2. sporadic (comparative more sporadic, superlative most sporadic) 1. a disease somewhat resembling the Asiatic cholera, but originating where it occurs, and rarely becoming epidemic. Trends of sporadic. In the genetic context, sporadic denotes a singleton or sport. [Medieval Latin sporadicus, scattered, from Greek sporadikos, from sporas, sporad-; see sper- in Indo-European roots.] Endemic refers to the constant presence and/or usual prevalence of a disease or infectious agent in a population within a geographic area. Throughout human history, there have been a number of pandemics of diseases such as smallpox and tuberculosis.The most fatal pandemic in recorded history was the Black Death (also known as The Plague), which killed an estimated 75–200 million people in the 14th century. Transmission The most common symptoms are fever, headache, and neck stiffness. The term was not used yet but was for later pandemics including the 1918 influenza pandemic (Spanish flu). Related to Sporadic: sporadic disease, sporadic fatal insomnia The following article is from The Great Soviet Encyclopedia (1979). Sporadic cholera synonyms, Sporadic cholera pronunciation, Sporadic cholera translation, English dictionary definition of Sporadic cholera. Sporadic colorectal cancer is the term given to those patients who are affected with the disease, but have no family history of this condition. An epidemic (from Greek ἐπί epi "upon or above" and δῆμος demos "people") is the rapid spread of disease to a large number of people in a given population within a short period of time. Definition of sporadic : occurring occasionally, singly, or in irregular or random instances sporadic protests a sporadic disease Other Words from sporadic Synonyms & Antonyms Choose the Right Synonym Sporadic Has Medieval Latin Roots More Example Sentences Learn More about sporadic Synonyms & Antonyms for sporadic The sporadic form of the disease, also known as sporadic Creutzfeldt-Jakob disease (CJD), or classical CJD, accounts for approximately 80% of all recognised prion disease. Outbreak data have been used to estimate the proportion of illnesses attributable to different foods. Times, Sunday Times (2010) Related word partners sporadic . Sporadic disease: See also: Sporadic Genetic Diseases: »Introduction: Sporadic Genetic Diseases »Symptoms of Sporadic Genetic Diseases The majority of cases are sporadic, and usually unilateral. Disclaimer. (archaic) (of diseases) occurring in isolated instances; not epidemic. a disease which occurs in single and scattered cases. See the Note under Endemic a. Information and translations of sporadic in the most comprehensive dictionary definitions resource on … The sound of sporadic shooting could still be heard. Several quite different and disparate phenomena are covered by this term, including a new mutation; occult nonpaternity; the chance outcome for a recessive trait in two carrier parents with a small family; extreme variability in the expression of a gene; an environmental phenocopy; a multilocal genocopy, etc. 2. See the Note under Endemic, a. Sporadic disease (Med) a disease which occurs in single and scattered cases. Hereditary nonpolyposis colorectal cancer (Lynch syndrome or HNPCC), an autosomal dominant disorder, is a disease in families where multiple members have colorectal and other forms of cancer. isolated, as a single instance of something; being or occurring apart from others. See … For specific diseases, see under the specific name, as addison's disease. The conflict ended in 2003 but its effects are still felt, with hundreds dying each day from diseases and sporadic attacks from rebel militia groups. 2015 March 12, Daniel Taylor, “Chelsea out of Champions League after Thiago Silva sends 10-man PSG through on away goals”, in The Guardian (London)‎: 2.1.1. What does sporadic mean? In group theory, a sporadic group is one of the 26 exceptional groups found in the classification of finite simple groups.. A simple group is a group G that does not have any normal subgroups except for the trivial group and G itself. Sporadic CJD occurs in every country with a remarkably similar incidence: approximately one person in … Meaning of sporadic. (epidemiology) An occurrence of a disease or disorder in a population at a frequency higher than that expected in a given time period. occurring singly or … In the genetic context, sporadic … a definite pathological process having a characteristic set of signs and symptoms. Cancer that is not due to inherited gene changes is called “sporadic cancer.” It is believed that most- perhaps 90%-of all cancers are sporadic. Sporadic disease (medical condition): Most genetic diseases are inherited from the parents, with different inheritance patterns depending on its dominance versus recessiveness and ...more. An EU study determined that "87% of cases were sporadic, 8% genetic, 5% iatrogenic and less than 1% variant." For example, in meningococcal infections, an attack rate in excess of 15 cases per 100,000 people for two consecutive weeks is considered an epidemic. There are eight different diseases that affect mammals that are caused by prions such as scrapie, bovine spongiform encephalopathy (mad cow disease) and Feline spongiform encephalopathy (FSE). For the term sporadic disease may also exist other definitions and meanings , the meaning and definition indicated above are indicative not be used for medical and legal or special purposes . adjective Sporadic occurrences of something happen at irregular intervals....a year of sporadic fighting over northern France. 2. Denoting a temporal pattern of disease occurrence in an animal or human population in which the disease occurs only rarely and without regularity. It was a stodgy, weary display from Mourinho’s team with only sporadicmoments when they threatened Salvatore Sirigu’s goal and their manager seemed bewildered a… Introduction: Sporadic disease Description of Sporadic disease. It may affect the whole body or any of its parts, and its etiology, pathology, and prognosis may be known or unknown. Multiple system atrophy (MSA) is a rare neurodegenerative disorder characterized by autonomic dysfunction, tremors, slow movement, muscle rigidity, and postural instability (collectively known as parkinsonism) and ataxia.This is caused by progressive degeneration of neurons in several parts of the brain including the basal ganglia, inferior olivary nucleus, and cerebellum. A widespread disease that affects many individuals in a population. In sporadic cases, the misfolding of the prion protein is a process which is hypothesized to occur as a result of the effects of aging on cellular machinery, explaining why the disease often appears later in life. A widespread disease that occurs infrequently and irregularly remarkably similar incidence: approximately one person …! Roots. as polio, cholera, smallpox and tuberculosis have historically caused sporadic epidemics devastating. 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